The University of �εδ���app clinician scientists found that indoor tanning can trigger serious and sometimes debilitating skin reactions when ultraviolet (UV) radiation interacts with common medicines, foods, cosmetics and underlying health conditions.

The team are also based within the National Institute for Health and Care Research (NIHR) �εδ���app Biomedical Research Centre (BRC) and Northen Care Alliance NHS Foundation Trust.

The review revealed cases ranging from painful blistering disorders and severe rashes to flare-ups of autoimmune diseases and allergy-like reactions occurring within minutes of UV exposure.

Some patients became so ill they required hospital treatment, specialist care and, in a small number of cases, surgery.

The researchers analysed 34 scientific studies published up to May 2025 and identified 67 documented cases of photosensitivity reactions linked to recreational sunbed use.

While sunbeds are already recognised as a cause of skin cancer, the researchers say many users remain unaware that UV exposure can also trigger unexpected reactions in susceptible individuals.

The study found that a wide range of common medications were linked to adverse reactions following sunbed use.

These included antibiotics, blood pressure medicines and painkillers, alongside creams and topical treatments applied directly to the skin.

Surprisingly, everyday foods were also implicated: compounds found naturally in celery, parsnips and lime juice were associated with painful skin reactions when handled or eaten before exposure to sunbed UV radiation.

In several cases, a visit to a tanning salon triggered the first sign that a person had an undiagnosed medical condition.

One of the most commonly reported disorders was pseudoporphyria, a blistering condition that closely resembles rare diseases caused by problems in the body's response to sunlight.

Researchers also identified cases of solar urticaria, a rare condition sometimes described as a sunlight allergy, which can cause hives and swelling within minutes of UV exposure.

The review found evidence that sunbed use may worsen symptoms in people living with systemic lupus erythematosus, or lupus, a long-term autoimmune disease known to be aggravated by ultraviolet radiation.

Young women accounted for most reported cases, although the researchers stress that anyone using a sunbed could potentially experience a photosensitivity reaction if they are vulnerable.

Professor of Dermatology and Photobiology and principal investigator said: “Most people know that sunbeds increase the risk of skin cancer, but our review shows that this is only part of the picture.

“We found evidence that UV radiation from sunbeds can trigger a surprisingly wide range of photosensitivity reactions, including severe blistering disorders, autoimmune flare-ups and reactions linked to commonly prescribed medicines. Some patients became ill enough to require hospital treatment.

“Perhaps most strikingly, sunbed exposure sometimes revealed an underlying health condition for the first time.”

Professor Rhodes, who is also lead for the Photodermatoses research programme within the NIHR �εδ���app BRC’s Dermatology Theme, added: “These findings underline the need for stronger public warnings and better education for both consumers and sunbed operators.

“And the public needs to be made aware of possible interactions between UV radiation and medicines, cosmetic products, foods and existing health conditions before deciding to use indoor tanning devices.

“Even a short sunbed session may be enough to provoke a serious reaction in susceptible individuals, highlighting yet another reason to think twice before seeking an artificial tan.”

• The paper Community sunbed use and photosensitivity reactions: a systematic review is published in the journal doi 10.1007/s43630-026-00928-7

The move follows recent studies which have shown communities of bacteria that live in the skin - known as the microbiome - are a more accurate predictor of age than the gut microbiome.

However, there is little knowledge on the processes involved in which the skin microbiome affects ageing.

Called Skin Microbiome in Healthy Ageing (SMiHA), the network is a multi-disciplinary UK research community comprising of universities, industry, and healthcare practitioners.

It is a jointly funded by the Biotechnology and Biological Sciences Research Council and the Medical Research Council.

It will study how changes in the composition of the skin microbiome reflect acceleration or deceleration of the ageing process and age specific disorders.

The network is led by Julie Thornton Professor of Cutaneous Biology and Director of the Centre for Skin Sciences, University of Bradford, and Scientific Director, Plastic Surgery and Burns Unit.

Other members of the network are from the University of Liverpool, Queen Mary University London and the University of East Anglia.

Around 50% of the UK population have a microbiome associated skin complaint, such as infant eczema or teenage acne each year. Management of infected wounds alone utilise 5.5% of total NHS expenditure.

Skin complaints are the most frequent problems seen by GPs, and poor skin health and chronic skin conditions, such as infected wounds, often impacts on the elderly.

Professor Andrew McBain a microbiologist from The University of �εδ���app said: “We formed this network to help skin microbiome research come up with solutions to age-related conditions.

“We hope to achieve that through creating more knowledge about the aging skin microbiome.

”We believe that this will create better outcomes and quality of life for many people.”

The network itself is a member of a the UK Ageing Network which encompasses 11 interdisciplinary research networks bringing researchers and stakeholders from different disciplines together to create new knowledge and better outcomes for older people.